Kaiju Killing Corps- Man vs Giant Beasts.These monsters usually have an Achilles' Heel - usually in the form of Applied Phlebotinum that is the only thing that can harm them (which our organization would exploit as weapons), or a certain weak point in their body, which is usually a core placed in a strategic part of its body. This doesn't mean they are invincible though.
Whatever their origin, they will always be Nigh-Invulnerable (or just Made of Iron) or have Healing Factor which makes them hard to kill. There will already be quite a lot of them already by the time the story kicks in. The monster's origin usually vary from being simply aliens (or Angels & Demons or Robots & Golems) to coming from a single Hellgate to being a result of Creating Life Gone Horribly Wrong to being a mutant strain of an existing lifeform or a beastly sort of Henchmen Race created by the Big Bad to simply just popping out of nowhere. Whatever their flavor, they're out to multiply and destroy, and our heroes' job is to stop them from doing so. Sometimes though, they are sentient but Always Chaotic Evil with little regard for self-preservation. The monsters are usually characterized by being non-sentient beasts that devour or destroy humans or resources which make them a direct threat. In verses that rely on Applied Phlebotinum, compatibility with the phlebotinum is the only requirement, and you usually cannot refuse to join them, especially if compatible people are rare. There usually isn't a prerequisite for its recruits as long as they can fight, they can join. They can be as large and publicized as the military, but an Oddly Small Organization or a small The Squad/ Five-Man Band would also do. The organization is usually the only one of its kind, but within a global reach there will often be "branches." Size and scope also vary. In cases where there is a Masquerade, their purpose is to uphold it by preventing muggles from discovering the existence of such monsters. The most basic form of this is that a certain organization is in charge of recruiting people and equipping them with a specific set of equipment and/or skills vital to exploiting the weaknesses of the monsters they are fighting. And thus begins the tale of their struggle. Humanity is at a disadvantage, but at some point, they discover their enemies' weakness, and now have a fighting chance. In a World note usually without The Masquerade where humanity is terrorized by a race of Nigh-Invulnerable behemoths.
A plot trope that involves a fantastic version of the most basic conflicts: Man vs.